Structure of PDB 5kue Chain A Binding Site BS02

Receptor Information
>5kue Chain A (length=95) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DDVTVVYQNGLPVISVRLPSRRERCQFTLKPISDSVGVFLRQLQEEDRGI
DRVAIYSPDGVRVAASTGMDLLLMDDFKLVINDLTYHVRPPKRDL
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5kue Chain A Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5kue Structural Insights into Mitochondrial Calcium Uniporter Regulation by Divalent Cations.
Resolution1.5 Å
Binding residue
(original residue number in PDB)		T76 V78 V85 S87
Binding residue
(residue number reindexed from 1)		T4 V6 V13 S15
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051560 mitochondrial calcium ion homeostasis

View graph for
Biological Process
External links
PDB RCSB:5kue, PDBe:5kue, PDBj:5kue
PDBsum5kue
PubMed27569754
UniProtQ8NE86|MCU_HUMAN Calcium uniporter protein, mitochondrial (Gene Name=MCU)

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