Structure of PDB 5kj4 Chain A Binding Site BS02

Receptor Information
>5kj4 Chain A (length=228) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGMPASRVRYRVD
DVQFPYPASIFDVEEDSGRVVTRVNLNEEPTTIFKLVVVAFDDGEPVMSS
SATVRILVLHPGEIPRFTQEEYRPPPVSELAARGTVVGVISAAAINQSIV
YSIVAGNEEDKFGINNVTGVIYVNSPLDYETRTSYVLRVQADSLEVVLAN
LRVPSKSNTAKVYIEIQDENDHPPVFLE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5kj4 Chain A Residue 2002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5kj4 An elastic element in the protocadherin-15 tip link of the inner ear.
Resolution3.35 Å
Binding residue
(original residue number in PDB)		E1026 E1077 D1115 E1116 D1118
Binding residue
(residue number reindexed from 1)		E129 E180 D218 E219 D221
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609 cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5kj4, PDBe:5kj4, PDBj:5kj4
PDBsum5kj4
PubMed27857071
UniProtQ99PJ1|PCD15_MOUSE Protocadherin-15 (Gene Name=Pcdh15)

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