Structure of PDB 5k5h Chain A Binding Site BS02
Receptor Information
>5k5h Chain A (length=111) Species:
9606
(Homo sapiens) [
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PFKCSMCDYASVEVSKLKRHIRSHTGERPFQCSLCSYASRDTYKLKRHMR
THSGEKPYECYICHARFTQSGTMKMHILQKHTENVAKFHCPHCDTVIARK
SDLGVHLRKQH
Ligand information
>5k5h Chain C (length=13) [
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cgccccctgctgg
Receptor-Ligand Complex Structure
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PDB
5k5h
Structural Basis for the Versatile and Methylation-Dependent Binding of CTCF to DNA.
Resolution
3.108 Å
Binding residue
(original residue number in PDB)
Y392 K395 Y407 S419 K423 K449 S450 R457
Binding residue
(residue number reindexed from 1)
Y43 K46 Y58 S70 K74 K100 S101 R108
Binding affinity
PDBbind-CN
: Kd=30nM
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5k5h
,
PDBe:5k5h
,
PDBj:5k5h
PDBsum
5k5h
PubMed
28529057
UniProt
P49711
|CTCF_HUMAN Transcriptional repressor CTCF (Gene Name=CTCF)
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