Structure of PDB 5k3q Chain A Binding Site BS02

Receptor Information
>5k3q Chain A (length=43) Species: 9544 (Macaca mulatta) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VDHCARHGEKLLLFCQEDSKVICWLCERSQEHRGHHTFLMEEV
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5k3q Chain A Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5k3q Crystal structure of the Trim5 alpha Bbox2 domain from rhesus macaques describes a plastic oligomerisation interface.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		C108 D111 H125 H128
Binding residue
(residue number reindexed from 1)		C15 D18 H32 H35
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:5k3q, PDBe:5k3q, PDBj:5k3q
PDBsum5k3q
PubMed27402535
UniProtQ0PF16|TRIM5_MACMU Tripartite motif-containing protein 5 (Gene Name=TRIM5)

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