Structure of PDB 5jlx Chain A Binding Site BS02

Receptor Information

>5jlx Chain A (length=57) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

GRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALSLTERQIKIWFQNRR
MKWKKEN

Ligand information

>5jlx Chain C (length=15) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

tctctaatggctttc

Receptor-Ligand Complex Structure

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PDB	5jlx Stereospecific Effects of Oxygen-to-Sulfur Substitution in DNA Phosphate on Ion Pair Dynamics and Protein-DNA Affinity.
Resolution	2.748 Å
Binding residue (original residue number in PDB)	R5 Q6 Y8 Q44 W48 N51
Binding residue (residue number reindexed from 1)	R2 Q3 Y5 Q41 W45 N48
Binding affinity	PDBbind-CN: Kd=7.3nM

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677	DNA binding

	Biological Process
GO:0006355	regulation of DNA-templated transcription

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Molecular Function

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Biological Process

External links

PDB	RCSB:5jlx, PDBe:5jlx, PDBj:5jlx
PDBsum	5jlx
PubMed	27271797
UniProt	P02833\|ANTP_DROME Homeotic protein antennapedia (Gene Name=Antp)

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