Structure of PDB 5jdq Chain A Binding Site BS02

Receptor Information
>5jdq Chain A (length=296) Species: 243232 (Methanocaldococcus jannaschii DSM 2661) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVILGVGYFLLGLILLYYGSDWFVLGSERIARHFNVSNFVIGATVMAIGT
SLPEILTSAYASYMHAPGISIGNAIGSCICNIGLVLGLSAIISPIIVDKN
LQKNILVYLLFVIFAAVIGIDGFSWIDGVVLLILFIIYLRWTVKNGSAEI
ENNPSVVFSLVLLIIGLIGVLVGAELFVDGAKKIALALDISDKVIGFTLV
AFGTSLPELMVSLAAAKRNLGGMVLGNVIGSNIADIGGALAVGSLFMHLP
AENVQMAVLVIMSLLLYLFAKYSKIGRWQGILFLALYIIAIASLRM
Ligand information
Ligand IDNA
InChIInChI=1S/Na/q+1
InChIKeyFKNQFGJONOIPTF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Na+]
FormulaNa
NameSODIUM ION
ChEMBL
DrugBankDB14516
ZINC
PDB chain5jdq Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5jdq Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		T50 S51 E54 T209 S210 E213
Binding residue
(residue number reindexed from 1)		T50 S51 E54 T204 S205 E208
Annotation score5
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005262 calcium channel activity
GO:0008273 calcium, potassium:sodium antiporter activity
Biological Process
GO:0006874 intracellular calcium ion homeostasis
GO:0035725 sodium ion transmembrane transport
GO:0055085 transmembrane transport
GO:0070588 calcium ion transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:5jdq, PDBe:5jdq, PDBj:5jdq
PDBsum5jdq
PubMed27183196
UniProtQ57556|Y091_METJA Uncharacterized membrane protein MJ0091 (Gene Name=MJ0091)

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