Structure of PDB 5jcf Chain A Binding Site BS02

Receptor Information
>5jcf Chain A (length=660) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GDLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKA
SEQGKVIVLVNKVPLVEQHLRKEFNPFLKHWYQVIGLSGDSELKISFPEV
VKRYDVIICTAQILENSLLNATEESVRLSDFSLIIIDQCHHTQKEGVYNN
IMRRYLKEKIKNRKQAKELIPQPQILGLTASPGVGGARSNSKAEEHILKI
CANLDACRIMTVKEHASQLKNQVKEPFKKTVIADDKRRDPFRERIIEIMQ
DIQKYCQLYPKSEFGSQPYEQWVIREERRAAKEEKRKERVCAEHLKKYND
ALQINDTIRMVDAYNHLNNFYKELKRRKTAESDDDSKQDETDEFLMRLFH
AKKKQLKELARKPEYDNEKLMKLRNTLMEEFTKTEEPRGIIFTKTRQSAL
ALYHWIMDNPKFEEVGIKAHFLIGAGHNSETKPMTQNEQREVIDKFRGGS
INLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRARADESTYAL
VASSGSGAVEREDVNIFRENMMYKAIRRVQEMPPEEYLNKIQDFQLQSIV
EKQMKAKRDQRITFLCKNCHKLICSGEDIQVIENMHHVSVKKDFQHLYHK
RENQTNVEIICKDCGQVWGNMMVYRGLDLPCLKIRNFVVAFEDTKEIFKK
WGELPIIFPD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5jcf Structural Analysis of dsRNA Binding to Anti-viral Pattern Recognition Receptors LGP2 and MDA5.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		N357 K358 V359 G385 T406 Q408 N412 K700 R702 G730 S735 T763 T764 V765 K977
Binding residue
(residue number reindexed from 1)		N61 K62 V63 G89 T110 Q112 N116 K394 R396 G424 S429 T457 T458 V459 K649
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:5jcf, PDBe:5jcf, PDBj:5jcf
PDBsum5jcf
PubMed27203181
UniProtD9N195

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