Structure of PDB 5ix1 Chain A Binding Site BS02

Receptor Information
>5ix1 Chain A (length=414) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVI
SDHICLTFTDNGNGMTADKLHKMLSFGFSDKVTMNGHVPVGLYGNGFKSG
SMRLGKDAMVFTKNGETMSVGFLSQTYLEVIKAEHVVVPIVTFNKHRQMI
NLTESKASLAAILEHSLFSTEQKLLAELNAIMGKKGTRIIIWNLRSYKNA
TEFDFEKDKYDIRIPEDYKKQEIAPESDYSLRAYCSILYLKPRMQIIIRG
QKVKTQLVSKSLAYIERDVYRPKFLTRTVRITFGFNCRNKDHYGIMMYHK
NRLIKAYEKVGCQNMGVGVVGIIECNFLKPTHNKQDFDYTNEYRLTILAL
GEKLNDYWNEMKKRPDQTWVQCDACLKWRKLPDGIDQLPEKWYCSNNPDP
QFRNCEVPEEPEDE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5ix1 Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5ix1 Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin
Resolution2.6 Å
Binding residue
(original residue number in PDB)		C413 C435 C446
Binding residue
(residue number reindexed from 1)		C372 C394 C405
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:5ix1, PDBe:5ix1, PDBj:5ix1
PDBsum5ix1
PubMed27528681
UniProtF7BJB9|MORC3_MOUSE MORC family CW-type zinc finger protein 3 (Gene Name=Morc3)

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