Structure of PDB 5igw Chain A Binding Site BS02

Receptor Information
>5igw Chain A (length=296) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKDIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLP
RREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAG
TIDHGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHTPE
EARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDVHA
GHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAYKE
IGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALEV
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5igw Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5igw Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance.
Resolution2.096 Å
Binding residue
(original residue number in PDB)		D219 T221
Binding residue
(residue number reindexed from 1)		D216 T218
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5igw, PDBe:5igw, PDBj:5igw
PDBsum5igw
PubMed28416110
UniProtO32553

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