Structure of PDB 5igv Chain A Binding Site BS02

Receptor Information
>5igv Chain A (length=298) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKDIKQVIEIAKKHNLFLKEETIQFNESGLDFQAVFAQDNNGIDWVLRLP
RREDVMPRTKVEKQALDLVNKYAISFQAPNWIIYTEELIAYKKLDGVPAG
TIDHNIGNYIWEIDINNVPELFHKSLGRVLAELHSIPSNKAAALDLVVHT
PEEARMSMKQRMDAVRAKFGVGENLWNRWQAWLNDDDMWPKKTGLIHGDV
HAGHTMIDKDANVTGLIDWTEAKVTDVSHDFIFNYRAFGEEGLEALILAY
KEIGGYYWPKMKEHIIELNAAYPVSIAEFALVSGIEEYEQMAKEALEV
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5igv Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5igv Structural Basis for Kinase-Mediated Macrolide Antibiotic Resistance.
Resolution1.55 Å
Binding residue
(original residue number in PDB)		D219 T221
Binding residue
(residue number reindexed from 1)		D218 T220
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5igv, PDBe:5igv, PDBj:5igv
PDBsum5igv
PubMed28416110
UniProtO32553

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