Structure of PDB 5h58 Chain A Binding Site BS02

Receptor Information

>5h58 Chain A (length=194) Species: 100226 (Streptomyces coelicolor A3(2)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

LRAEQTRATIIGAAADLFDRRGYESTTLSEIVAHAGVTKGALYFHFAAKE
DLAHAILEIQSRTSRRLAKDLDGRGYSSLEALMRLTFGMARLCVQGPVLR
AGLRLATAPVRPPLPHPFTEWREIATSRLLDAVRQSDVHQDIDVDSVAHT
LVCSVVGTREPRRLAEMWYILIRGMVPVTRRARYVTLAARLEQE

Ligand information

>5h58 Chain F (length=22) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ctcaacagaccgtgccgcctgc

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5h58 Structural and dynamics studies of the TetR family protein, CprB from Streptomyces coelicolor in complex with its biological operator sequence
Resolution	3.991 Å
Binding residue (original residue number in PDB)	T31 L32 S33 Y47 A52 K53
Binding residue (residue number reindexed from 1)	T27 L28 S29 Y43 A48 K49

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0000976	transcription cis-regulatory region binding
GO:0003677	DNA binding
GO:0003700	DNA-binding transcription factor activity

	Biological Process
GO:0006355	regulation of DNA-templated transcription

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Biological Process

External links

PDB	RCSB:5h58, PDBe:5h58, PDBj:5h58
PDBsum	5h58
PubMed	28343010
UniProt	Q7AKF2

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