Structure of PDB 5h43 Chain A Binding Site BS02
Receptor Information
>5h43 Chain A (length=428) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
NQGTVNWSVDDIVKGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAG
LIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFIS
LLASPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVPDMS
SLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHHDDPEVLA
DTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGN
IVTGTDEQTQVVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQ
IQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHC
GIIEPLMNLLTAKDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGG
LDKIEALQNHENESVYKASLSLIEKYFS
Ligand information
>5h43 Chain C (length=15) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
SELAEQPERKITRNQ
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
5h43
Structural insights into the nuclear import of the histone acetyltransferase males-absent-on-the-first by importin alpha 1
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
S105 W142 N146 S149 G150 T155 W184 N188 G191 D192 W231 R238 N239 P265 W273 P308 T311
Binding residue
(residue number reindexed from 1)
S36 W73 N77 S80 G81 T86 W115 N119 G122 D123 W162 R169 N170 P196 W204 P239 T242
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5h43
,
PDBe:5h43
,
PDBj:5h43
PDBsum
5h43
PubMed
28991411
UniProt
P52292
|IMA1_HUMAN Importin subunit alpha-1 (Gene Name=KPNA2)
[
Back to BioLiP
]
