Structure of PDB 5h1w Chain A Binding Site BS02

Receptor Information
>5h1w Chain A (length=270) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMKLSLVISTSDAAFDALAFKGDLRKGMELAKRVGYQAVEIAVRDPSIVD
WNEVKILSEELNLPICAIGTGQAYLADGLSLTHPNDEIRKKAIERVVKHT
EVAGMFGALVIIGLVRGRREGRSYEETEELFIESMKRLLELTEHAKFVIE
PLNRYETDFINTIDDALRILRKINSNRVGILADTFHMNIEEVNIPESLKR
AGEKLYHFHVADSNRWAPGCGHFDFRSVFNTLKEIGYNRYVSVECLPLPG
GMEEAAEIAFKTLKELIIKL
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain5h1w Chain A Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5h1w TM0416, a Hyperthermophilic Promiscuous Nonphosphorylated Sugar Isomerase, Catalyzes Various C5and C6Epimerization Reactions
Resolution1.631 Å
Binding residue
(original residue number in PDB)		E149 D182 H208 E243
Binding residue
(residue number reindexed from 1)		E150 D183 H209 E244
Annotation score1
Enzymatic activity
Enzyme Commision number 5.1.3.-
5.3.1.-
Gene Ontology
Molecular Function
GO:0016853 isomerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006020 inositol metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5h1w, PDBe:5h1w, PDBj:5h1w
PDBsum5h1w
PubMed28258150
UniProtQ9WYP7|IOLO_THEMA 5-keto-L-gluconate epimerase (Gene Name=iolO)

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