Structure of PDB 5eyn Chain A Binding Site BS02

Receptor Information

>5eyn Chain A (length=306) Species: 345073 (Vibrio cholerae O395)

MSRVWLTGDAVVDLIPDGQQHYLKCPGGAPANVAVAIARLSGRSAFFGRV
GNDPFGRFMQQTLTDEQVDCQHLHFDPVHRTSTVVVDLDEHGERSFTFMV
KPSADQFLQLSDIPSFQKGEWLHVCSIALANQPSRSSTFAAIAQMKEVGG
YVSFDPNLREEVWSEPQELQATVMRAVGLADVVKFSEEELQFLTGTQSIE
EGLQAIADFQIPLVVVTLGAKGALVATPNSQQIVSGKAVKPIDTTGAGDA
FVGGLLYRLSVAQDWHNQATILDAVKWANGCGALATTQKGAMTALPNQAA
LYAFLE

Ligand information

• Ligand ID: BEF
• InChI: InChI=1S/Be.3FH/h;3*1H/q+2;;;/p-3
• InChIKey: OGIAHMCCNXDTIE-UHFFFAOYSA-K
• SMILES:
  OpenEye OEToolkits 1.5.0: [Be-](F)(F)F
  ACDLabs 10.04
  CACTVS 3.341: F[Be-](F)F
• Formula: Be F3
• Name: BERYLLIUM TRIFLUORIDE ION
• PDB chain: 5eyn Chain A Residue 403

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5eyn Cloning, expression, purification, crystallization and preliminary X-ray analysis of a fructokinase from Vibrio cholerae O395
• Resolution: 1.289 Å
• Binding residue (original residue number in PDB): G263 G265 D266
• Binding residue (residue number reindexed from 1): G246 G248 D249
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): G263 A264 G265 D266
• Catalytic site (residue number reindexed from 1): G246 A247 G248 D249
• Enzyme Commision number: 2.7.1.4: fructokinase.

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0008865 fructokinase activity
• GO:0016301 kinase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0006000 fructose metabolic process
• GO:0016310 phosphorylation
• GO:0046835 carbohydrate phosphorylation

External links

• PDB: RCSB:5eyn, PDBe:5eyn, PDBj:5eyn
• PDBsum: 5eyn
• UniProt: A0A0H3AER7