Structure of PDB 5epl Chain A Binding Site BS02

Receptor Information
>5epl Chain A (length=54) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSEHVFAVESIEKKRIRKGRVEYLVKWRGWSPKYNTWEPEENILDPRLLI
AFQN
Ligand information
Receptor-Ligand Complex Structure
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PDB5epl A cellular chemical probe targeting the chromodomains of Polycomb repressive complex 1.
Resolution1.81 Å
Binding residue
(original residue number in PDB)
L49 P51
Binding residue
(residue number reindexed from 1)
L44 P46
Enzymatic activity
Enzyme Commision number 2.3.2.-
Gene Ontology
Biological Process
GO:0045892 negative regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:5epl, PDBe:5epl, PDBj:5epl
PDBsum5epl
PubMed26807715
UniProtO00257|CBX4_HUMAN E3 SUMO-protein ligase CBX4 (Gene Name=CBX4)

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