Structure of PDB 5ejz Chain A Binding Site BS02

Receptor Information
>5ejz Chain A (length=728) Species: 272943 (Cereibacter sphaeroides 2.4.1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VVPVLLFLLWVALLVPFGLLAAAPVAPSAQGLIALSAVVLVALLKPFADK
MVPRFLLLSAASMLVMRYWFWRLFETLPPPALDASFLFALLLFAVETFSI
SIFFLNGFLSADPTDRPFPRPLQPEELPTVDILVPSYNEPADMLSVTLAA
AKNMIYPARLRTVVLCDDGGTDQRCMSPDPELAQKAQERRRELQQLCREL
GVVYSTRERNEHAKAGNMSAALERLKGELVVVFDADHVPSRDFLARTVGY
FVEDPDLFLVQTPHFFINPDPIQRNLALGDRCPPENEMFYGKIHRGLDRW
GGAFFCGSAAVLRRRALDEAGGFAGETITEDAETALEIHSRGWKSLYIDR
AMIAGLQPETFASFIQQRGRWATGMMQMLLLKNPLFRRGLGIAQRLCYLN
SMSFWFFPLVRMMFLVAPLIYLFFGIEIFVATFEEVLAYMPGYLAVSFLV
QNALFARQRWPLVSEVYEVAQAPYLARAIVTTLLRPRSARFAVTAKDETL
SENYISPIYRPLLFTFLLCLSGVLATLVRWVAFPGDRSVLLVVGGWAVLN
VLLVGFALRAVAEKQQRRAAPRVQMEVPAEAQIPAFGNRSLTATVLDAST
SGVRLLVRLPGVGDPHPALEAGGLIQFQPKFPDAPQLERMVRGRIRSARR
EGGTVMVGVIFEAGQPIAVRETVAYLIFGESAHWRTMREATMRPIGLLHG
MARILWMAAASLPKTARDFMDEPARRRR
Ligand information
Ligand IDBGC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1
InChIKeyWQZGKKKJIJFFOK-VFUOTHLCSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.370OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O
CACTVS 3.370OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
OpenEye OEToolkits 1.7.6C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
ACDLabs 12.01OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namebeta-D-glucopyranose;
beta-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL1614854
DrugBankDB02379
ZINCZINC000003833800
PDB chain5ejz Chain C Residue 8 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5ejz Observing cellulose biosynthesis and membrane translocation in crystallo.
Resolution2.94 Å
Binding residue
(original residue number in PDB)		Y433 G437 I438 E439 V551
Binding residue
(residue number reindexed from 1)		Y421 G425 I426 E427 V539
Annotation score1
Enzymatic activity
Enzyme Commision number 2.4.1.12: cellulose synthase (UDP-forming).
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0005515 protein binding
GO:0016757 glycosyltransferase activity
GO:0016758 hexosyltransferase activity
GO:0016759 cellulose synthase activity
GO:0016760 cellulose synthase (UDP-forming) activity
GO:0035438 cyclic-di-GMP binding
Biological Process
GO:0006011 UDP-glucose metabolic process
GO:0030244 cellulose biosynthetic process
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5ejz, PDBe:5ejz, PDBj:5ejz
PDBsum5ejz
PubMed26958837
UniProtQ3J125

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