Structure of PDB 5ege Chain A Binding Site BS02

Receptor Information
>5ege Chain A (length=392) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RKLLVLLLDGFRSDYISEDALASLPGFREIVNRGVKVDYLTPDFPSLSYP
NYYTLMTGRHCEVHQMIGNYMWDPRTNKSFDIGVNRDSLMPLWWNGSEPL
WITLMKARRKVYMYYWPGCEVEILGVRPTYCLEYKTVPTDINFANAVSDA
LDSLKSGRADLAAIYHERIDVEGHHYGPSSPQRKDALRAVDTVLKYMIQW
IQDRGLQQDLNVILFSDHGMTDIFWMDKVIELSNYISLDDLQQVKDRGPV
VSLWPVPGKHSEIYHKLRTVEHMTVYEKESIPNRFYYKKGKFVSPLTLVA
DEGWFIAESREMLPFWMNSTGKREGWQRGWHGYDNELMDMRGIFLAIGPD
FKSNFRAAPIRSVDVYNIMAHVAGITPLPNNGSWSRVVSMLK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5ege Chain A Residue 508 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5ege Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase
Resolution2.0 Å
Binding residue
(original residue number in PDB)		D193 H197 H354
Binding residue
(residue number reindexed from 1)		D170 H174 H331
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.4.-
3.1.4.38: glycerophosphocholine cholinephosphodiesterase.
External links
PDB RCSB:5ege, PDBe:5ege, PDBj:5ege
PDBsum5ege
PubMed26888014
UniProtQ8BGN3|ENPP6_MOUSE Glycerophosphocholine cholinephosphodiesterase ENPP6 (Gene Name=Enpp6)

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