Structure of PDB 5ee3 Chain A Binding Site BS02

Receptor Information

>5ee3 Chain A (length=357) Species: 39947 (Oryza sativa Japonica Group)

ERPILGRFSSHLKIGIVGLPNVGKSTFFNIVTKLSIPAENFPFCTIDPNE
ARVYVPDERFDWLCQLYKPKSEVSAYLEINDIALGNAFLSHIRAVDGIFH
VLRAFEDKDSVDPVRDLETIGEELRLKDIEFVQNKIDDLEKSMKRSNDKQ
LKLEHELCEKVKAHLEDGKDVRFGDWKSADIEILNTFQLLTAKPVVYLVN
MSEKDYQRKKNKFLPKIHAWVQEHGGETIIPFSCAFERLLADMPPDEAAK
YCAENQIASVIPKIIKTGFAAIHLIYFFTAGPDEVKCWQIRRQTKAPQAA
GTIHTDFERGFICAEVMKFDDLKELGSESAVKAAGKYRQEGKTYVVQDGD
IIFFKFN

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 5ee3 Chain A Residue 402

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5ee3 ATP binding by the P-loop NTPase OsYchF1 (an unconventional G protein) contributes to biotic but not abiotic stress responses
• Resolution: 2.9 Å
• Binding residue (original residue number in PDB): S38 D94
• Binding residue (residue number reindexed from 1): S25 D81
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 3.6.5.-

Gene Ontology

Molecular Function

• GO:0003924 GTPase activity
• GO:0005515 protein binding
• GO:0005524 ATP binding
• GO:0005525 GTP binding
• GO:0016787 hydrolase activity
• GO:0016887 ATP hydrolysis activity
• GO:0043023 ribosomal large subunit binding
• GO:0046872 metal ion binding

Biological Process

• GO:0009651 response to salt stress
• GO:1900425 negative regulation of defense response to bacterium
• GO:1901001 negative regulation of response to salt stress

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005886 plasma membrane

External links

• PDB: RCSB:5ee3, PDBe:5ee3, PDBj:5ee3
• PDBsum: 5ee3
• PubMed: 26912459
• UniProt: Q6Z1J6|OLA1_ORYSJ Obg-like ATPase 1 (Gene Name=YCHF1)