Structure of PDB 5e5o Chain A Binding Site BS02

Receptor Information
>5e5o Chain A (length=294) Species: 771870 (Sordaria macrospora k-hell) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KLNPWAVVGFIDAEGSFMVRVRKNSKYKTGWLVVAIFSVTVDKKDLFLLE
SLKTFFGGLGSIKKSGNSTFSYRIESSEQLTKIILPFFDKYSLITEKLGD
YLLFKKVLELMGTKEHLTQRGLEKIVSLKASINKGLSEELQAAFPQCVPT
PRPEINNKNIPDPFWLAGFVSGDGSFKSILKKSESIKVGFQSILVFQITQ
HARDVKLMESLISYLGCGFIEKDSRGPWLYYTVTNFSDIQGKIIPFFHQY
KIIGSKYGDYMDWCKIALIMQNKNHLTPEGLNEIRALKGGMNKG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5e5o The Structural Basis of Asymmetry in DNA Binding and Cleavage as Exhibited by the I-SmaMI LAGLIDADG Meganuclease.
Resolution2.36 Å
Binding residue
(original residue number in PDB)		K32 Y33 K34 K69 S71 E81 S82 S83 H122 D179 S181 K183 L186 K187 T205 H207 W234 N298
Binding residue
(residue number reindexed from 1)		K26 Y27 K28 K63 S65 E75 S76 S77 H116 D173 S175 K177 L180 K181 T199 H201 W228 N292
Binding affinityPDBbind-CN: Kd~150nM
Enzymatic activity
Catalytic site (original residue number in PDB) G178 D179
Catalytic site (residue number reindexed from 1) G172 D173
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity

View graph for
Molecular Function
External links
PDB RCSB:5e5o, PDBe:5e5o, PDBj:5e5o
PDBsum5e5o
PubMed26705195
UniProtF7WD42

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