Structure of PDB 5dwb Chain A Binding Site BS02

Receptor Information
>5dwb Chain A (length=278) Species: 53501 (Thalassovita gelatinovora) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRLDLDFGRGLVAHVMLDNVSEEQYQQISDYFVPLVNKPKLKSRDAIGQA
FVMATEVCPDANPSDLWHHVLYRIYIREKIGTDPSQSWVRTSGEAFEVAL
VERYNPVLARHGIRLTALFKGQKGLALTRMGVADRVGSRKVDVMIEKQGG
GRSPDAEGFGVVGGIHAKVSLAERVSDDIPASRIMMGEGLLSVLSTLDVK
SFPPPHGDLVNRGELGTPDRPSDKRNYIEGHGDFSACFSYNLRTSPSNAT
TPSGRHIYVSGFSGQDDEFTDYLVAQLA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5dwb Restriction endonuclease AgeI is a monomer which dimerizes to cleave DNA.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		Y72 V89 R90 G93 K168 V169 S170 R174 K200 P203
Binding residue
(residue number reindexed from 1)		Y72 V89 R90 G93 K168 V169 S170 R174 K200 P203
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5dwb, PDBe:5dwb, PDBj:5dwb
PDBsum5dwb
PubMed28039325
UniProtQ9KHV6|T2A1_THAGE Type II restriction enzyme AgeI (Gene Name=ageIR)

[Back to BioLiP]