Structure of PDB 5dob Chain A Binding Site BS02

Receptor Information
>5dob Chain A (length=237) Species: 10360 (Human herpesvirus 5 strain AD169) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPLGSMLKLSELHDVFQRHPELELKYLNMMKMAITGKESICLPFNFHSHR
QHTCLDISPYGNEQVSRIACTSCEDNRILPTASDAMVAFINQTSNIMKNR
NFYYGFCKSSELLKLSTNQPPIFQIYYLLHAANHDIVPFMHAEDGRLHMH
VIFENPDVHIPCDCITQMLTAAREDYSVTLNIVRDHVVISVLCHAVSASS
VKIDVTILQRKIDEMDIPNDVSESFERYKELIQELCQ
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5dob Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5dob Unexpected features and mechanism of heterodimer formation of a herpesvirus nuclear egress complex.
Resolution2.47 Å
Binding residue
(original residue number in PDB)		M58 E63
Binding residue
(residue number reindexed from 1)		M6 E11
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0046765 viral budding from nuclear membrane
GO:0046802 exit of virus from host cell nucleus by nuclear egress

View graph for
Biological Process
External links
PDB RCSB:5dob, PDBe:5dob, PDBj:5dob
PDBsum5dob
PubMed26511021
UniProtP16794|NEC1_HCMVA Nuclear egress protein 1 (Gene Name=NEC1)

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