Structure of PDB 5dah Chain A Binding Site BS02

Receptor Information
>5dah Chain A (length=179) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIGGCCVCSDERGWAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWFCRK
CESQERAARVRCELCPHKDGALKRTDNGGWAHVVCALYIPEVQFANVSTM
EPIVLQSVPHDRYNKTCYICDEQGRESKAATGACMTCNKHGCRQAFHVTC
AQFAGLLCEEEGNGADNVQYCGYCKYHFS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5dah Chain A Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5dah The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.
Resolution2.611 Å
Binding residue
(original residue number in PDB)		C25 C28 H52 C55
Binding residue
(residue number reindexed from 1)		C5 C8 H32 C35
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5dah, PDBe:5dah, PDBj:5dah
PDBsum5dah
PubMed26439302
UniProtP55197|AF10_HUMAN Protein AF-10 (Gene Name=MLLT10)

[Back to BioLiP]