Structure of PDB 5cyx Chain A Binding Site BS02

Receptor Information
>5cyx Chain A (length=318) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NSPPSFGVNMTLVTLPEDLPVGAVAFWLVATLTYGISGPNASYFSVNANT
GEVKLASPLDFETVPFFKITISTSDGLNIRTAEMQVIVEDRNDNIPVFLN
TEFSTSINETLPVGSVVFSVLAEDKDTGTAGLVQYFIEKVIPSTANSNNL
FRILENGSIVLNDTLSYNNKSAFYQLELKACDSGGILDNKPKTQCSQPVF
VSISVIDEPDLDPRFIREFYSASVAEDATLGTSVLTVEAVDSDKGINDIV
TYSVSNSTRPGWFDIREDGVIFVNGSLDREQLLLENEEVQIQVTATEKNL
NIYGQEAKASMWVTIRVT
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5cyx Chain A Residue 1002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5cyx Crystal Structure of Mouse Protocadherin-24 EC1-3
Resolution2.1 Å
Binding residue
(original residue number in PDB)
E17 E68 D96 R97 D99 D132
Binding residue
(residue number reindexed from 1)
E17 E62 D90 R91 D93 D126
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0098609 cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5cyx, PDBe:5cyx, PDBj:5cyx
PDBsum5cyx
PubMed
UniProtE9Q7P9|CDHR2_MOUSE Cadherin-related family member 2 (Gene Name=Cdhr2)

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