Structure of PDB 5cnq Chain A Binding Site BS02

Receptor Information
>5cnq Chain A (length=392) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GIKGIYKEIGSGERISLCKLAIDHLEQHNRPLRLAIDMAIWQFQIQAARG
GSNPAIRTLFYRFVRLLSLGIHPIFVFDGPNKPGVSTAMAKRLIRLFGFT
AHDAPGEAEAECAYLEQQGIVDAVLSEDVDTIMFGSRVTLRDWSSEGGPP
THVTLHDAKKIAEGPSGLDREGMVLVALMSGGGIPGCGIKVACQAAKAGF
GKELCAITEWKQRLLHELRTNESGFFRTKHKALEIPENFPNMEVLRYYTH
PVVSSPATIERLRQEFPPSSTVDIAGLREFTRETFDWTFRPGAIKLIKVL
APGLLVQRCLDRYEESTLVKGISMRREHFSTDATPELRVSFIPAELVGLD
PGQEPEVKPFDPWQPDLAWVPETILKLGVPVTVEDWEEGQRS
Ligand information
Receptor-Ligand Complex Structure
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PDB5cnq Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA.
Resolution2.602 Å
Binding residue
(original residue number in PDB)
Y7 D141 T257 K258 A261
Binding residue
(residue number reindexed from 1)
Y6 D128 T228 K229 A232
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004518 nuclease activity
GO:0008821 crossover junction DNA endonuclease activity

View graph for
Molecular Function
External links
PDB RCSB:5cnq, PDBe:5cnq, PDBj:5cnq
PDBsum5cnq
PubMed26686639
UniProtG0RYN2

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