Structure of PDB 5cmc Chain A Binding Site BS02

Receptor Information
>5cmc Chain A (length=247) Species: 27923 (Mnemiopsis leidyi) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LIGRHLRLGSVESQPFMFFATEGCEGNDCWSGMVNDMVVKLSEDLGFTYE
YIQPDDRKFGALNKTTNEWNGMIRDLLDDKTDMIAIDLSTNSARKSAIDY
SFPFMDAGIKAVVKGEGTTLNQVLELLDQDKYKWGVIGSRHPETLLKTHR
DSRYSRLVDEGVELKDLNHAIETLRGGLFVFIDEGPVLAHNLISDCDVFS
VGEEFQSFEYAFGLPKDSPYKSLIDSHLLKFREEGFIDILWEKWSSG
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain5cmc Chain B Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5cmc Molecular lock regulates binding of glycine to a primitive NMDA receptor.
Resolution1.28 Å
Binding residue
(original residue number in PDB)		D110 E213
Binding residue
(residue number reindexed from 1)		D106 E209
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
GO:0046872 metal ion binding
Biological Process
GO:0034220 monoatomic ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5cmc, PDBe:5cmc, PDBj:5cmc
PDBsum5cmc
PubMed27791085
UniProtA0A0R4I973

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