Structure of PDB 5ciu Chain A Binding Site BS02
Receptor Information
>5ciu Chain A (length=127) Species:
9606
(Homo sapiens) [
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EYQDGKEFGIGDLVWGKIKGFSWWPAMVVSWKATSKRQAMSGMRWVQWFG
DGKFSEVSADKLVALGLFSQHFNLATFNKLVSYRKAMYHALEKARVRAGK
TFDQLKPMLEWAHGGFKPTGIEGLKPN
Ligand information
>5ciu Chain D (length=7) Species:
9606
(Homo sapiens) [
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TGGVKKP
Receptor-Ligand Complex Structure
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PDB
5ciu
Structural basis for recognition of histone H3K36me3 nucleosome by human de novo DNA methyltransferases 3A and 3B.
Resolution
2.24 Å
Binding residue
(original residue number in PDB)
K234 F236 W239 K251 W263 D266 K268 F269
Binding residue
(residue number reindexed from 1)
K19 F21 W24 K36 W48 D51 K53 F54
Enzymatic activity
Enzyme Commision number
2.1.1.37
: DNA (cytosine-5-)-methyltransferase.
External links
PDB
RCSB:5ciu
,
PDBe:5ciu
,
PDBj:5ciu
PDBsum
5ciu
PubMed
26993463
UniProt
Q9UBC3
|DNM3B_HUMAN DNA (cytosine-5)-methyltransferase 3B (Gene Name=DNMT3B)
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