Structure of PDB 5cg9 Chain A Binding Site BS02
Receptor Information
>5cg9 Chain A (length=267) Species:
5762
(Naegleria gruberi) [
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HMINKKSLLQNLLSKCKTTFQQSFTNANITLKDEKWLKNVRTAYFVCDHD
GSVELAYLPNVLPKELVEEFTEKFESIQTGRKKDTGYSGILDNSMPFNYV
TADLSQELGQYLSEIVNPQINYYISKLLTCVSSRTINYLVSLNDSYYALN
NCLYPSTAFNSLKPSNDGHRIRKPHKDNLDITPSSLFYFGNFQNTEGYLE
LTDKNCKVFVQPGDVLFFKGNEYKHVVANITSGWRIGLVYFAHKGSKTKP
YYEDTQKNSLKIHKETK
Ligand information
>5cg9 Chain C (length=13) [
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tgtcagcgcatgg
Receptor-Ligand Complex Structure
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PDB
5cg9
Structure of Naegleria Tet-like dioxygenase (NgTet1) in complexes with a reaction intermediate 5-hydroxymethylcytosine DNA.
Resolution
2.693 Å
Binding residue
(original residue number in PDB)
Y141 N147 Y153 T155 A156 R224 V293 F295 H297 Q310
Binding residue
(residue number reindexed from 1)
Y87 N93 Y99 T101 A102 R170 V239 F241 H243 Q256
Enzymatic activity
Enzyme Commision number
1.14.11.80
: methylcytosine dioxygenase.
External links
PDB
RCSB:5cg9
,
PDBe:5cg9
,
PDBj:5cg9
PDBsum
5cg9
PubMed
26323320
UniProt
D2W6T1
|TET1_NAEGR Tet-like dioxygenase 1 (Gene Name=TET1)
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