Structure of PDB 5brm Chain A Binding Site BS02
Receptor Information
>5brm Chain A (length=154) Species:
9606
(Homo sapiens) [
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DLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGT
NIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPFPKNFMSVAKTILKRLFR
VYAHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQEL
IEKL
Ligand information
>5brm Chain M (length=17) Species:
9606
(Homo sapiens) [
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KRNATSPQVQRPSFMDY
Receptor-Ligand Complex Structure
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PDB
5brm
Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signaling.
Resolution
2.651 Å
Binding residue
(original residue number in PDB)
V62 N66 N69 Y72 D116 Q123 L126 D127
Binding residue
(residue number reindexed from 1)
V11 N15 N18 Y21 D65 Q72 L75 D76
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5brm
,
PDBe:5brm
,
PDBj:5brm
PDBsum
5brm
PubMed
26108669
UniProt
Q9H8S9
|MOB1A_HUMAN MOB kinase activator 1A (Gene Name=MOB1A)
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