Structure of PDB 5a31 Chain A Binding Site BS02

Receptor Information
>5a31 Chain A (length=1441) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIAARDLQEFVPFGRDHCKHHPNALNLQLRQLQPASEAAAAAGAAAAAKE
SWQLRKAVSEIGEDVDYDEELYVAGNMVIWSKGSKSQALAVYKAFTVDSP
VQQALWCDFIISEVEKCICILQSSCINMHSIEGKDYIASLPFQVANVWPT
KYGLLFERSPLPTMFSMLHPLDEITPLVCKAQYVVDHAMKIVFLNTDPSI
VMTYDAVQNVHSVWTLRRVKAEEEAAAAAAAAAGGFAAAAPIVPELCIDH
LWAAAQASKVFITSDLCGQKFLCFLVESQLQLRCVKFQESTALIFGSVTN
IPAKDAAPVEKIDTMLVLEGSGNLVLYTGVVRVGKVFIPATYIHSIRDPV
HNRVTLELSNGSMVRITIPEIATSELVQTCLQAIKFILPKEIAVQMLVKW
YNVHSAPGGASYHSEWNLFVTCLMNMMGYTHIPAIFFVLHLVYEELKLNT
LMGEGICSLVELLVQLARDLKLGPYVDHYYRDYPTLASEPPSIYQWVSSC
LKGEGAPPYPYLPGICERSRLVVLSIALYILSSLAERLVVWMTNVGFILR
DLETLPFGIALPIRDAIYHCREQPASDWPEAVCLLIGRQDLSAADDGMND
MNHEVMSLIWSEDLRVQDVRRLLQSAHPVRVNVVQYPELSEHEFIEEKEN
RLLQLCQRTMALPVGRGMFTLFSYHPVPTEPLPIPKLNLTGRAPPRNTTV
DLNSGNIDVPPNMTSWASFHNGVAAGLKIAPASQIDSAWIVYNKPKHAEL
ANEYAGFLMALGLNGHLTKLATLNIHDYLTKGHEMTSIGLLLGVSAAKLG
TMDMSITRLLSIHIPALLPPTSTELDVPHNVQVAAVVGIGLVYQGTAHRH
TAEVLLAEIGRPPGPEMEYATDRESYSLAAGLALGMVCLGHGSNLIGMSA
LNVPEQLYQYMVGGHSPSYQIKEGDTLNVDVTCPGATLALAMIYLKTNNR
SIADWLRAPDTMYLLDFVKPEFLLLRTLARCLILWDDILPNSKWVDSNVP
QIIRENLNLETLSQAHVYIIAGACLSLGFRFAGSENLSAFNCLHKFAKDF
MTYLSAPNASVTGPHNLETCLSVVLLSLAMVMAGSGNLKVLQLCRFLHMK
TGGEMNYGFHLAHHMALGLLFLGGGRYSLSTSNSSIAALLCALYPHFPAH
STDNRYHLQALRHLYVLAAEPRLLVPVDVDTNTPCYALLEVLYKGTQWYE
QTKEELMAPTLLPELHLLKQIKVKGPRYWELLIDLTQHLKSILSKDGVLY
VKLRAGQLSYKEDASEARAFKSAFTSDPALLSFAEYFCKPTVNMGQKQEI
LDLFSSVLYECVTQETPEMLPAYIAMDQAIRRLGRREMSETSELWQIKLV
LEFFSSRSHQFMNSEFLPVVKCTIDNTLDQWLQVGGDMCVHAYLSPLESQ
LSMLACFAVYHSVPAPAAAAAAAAAAAAAAAAAAAAAAAAA
Ligand information
>5a31 Chain W (length=25) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
MLRRKPTRLELKLDDIEEFENIRKD
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5a31 Atomic Structure of the Apc/C and its Mechanism of Protein Ubiquitination.
Resolution4.3 Å
Binding residue
(original residue number in PDB)		S1317 N1320
Binding residue
(residue number reindexed from 1)		S899 N902
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0005680 anaphase-promoting complex

View graph for
Cellular Component
External links
PDB RCSB:5a31, PDBe:5a31, PDBj:5a31
PDBsum5a31
PubMed26083744
UniProtQ9H1A4|APC1_HUMAN Anaphase-promoting complex subunit 1 (Gene Name=ANAPC1)

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