Structure of PDB 5a07 Chain A Binding Site BS02

Receptor Information
>5a07 Chain A (length=395) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DHDAEVLDSIMDRLHEPLYEKDTFDPNEVLAENKQLYEEFLLQEISEPKV
DNLVRSGDPLAGKAKGTILSLVRNSDLEDIISSIQQLEEEYNKNFGYPYT
FLNDEEFTDEFKDGIKSILPKDRVVEFGTIGPDNWNMPDSIDRERYDQEM
DKMSKENIQYAEVESYHNMCRFYSKEFYHHPLLSKYKYVWRLEPNVNFYC
KINYDVFQFMNKNDKIYGFVLNLYDSPQTIETLWTSTMDFVEEHPNYLNV
NGAFAWLKDNSQNPKNYDYTQGYSTCHFWTNFEIVDLDFLRSEPYEKYMQ
YLEEKGGFYYERWGDAPVRSLALALFADKSSIHWFRDIGYHHTPYTNCPT
CPADSDRCNGNCVPGKFTPWSDLDNQNCQATWIRHSMSEEELEMY
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain5a07 Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5a07 Structure of the Glycosyltransferase Ktr4P from Saccharomyces Cerevisiae
Resolution1.9 Å
Binding residue
(original residue number in PDB)		E262 H411
Binding residue
(residue number reindexed from 1)		E193 H342
Annotation score4
Enzymatic activity
Enzyme Commision number 2.4.1.-
Gene Ontology
Molecular Function
GO:0000026 alpha-1,2-mannosyltransferase activity
GO:0000030 mannosyltransferase activity
GO:0016757 glycosyltransferase activity
Biological Process
GO:0000032 cell wall mannoprotein biosynthetic process
GO:0006486 protein glycosylation
GO:0006487 protein N-linked glycosylation
GO:0006493 protein O-linked glycosylation
GO:0097502 mannosylation
Cellular Component
GO:0000324 fungal-type vacuole
GO:0005794 Golgi apparatus
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5a07, PDBe:5a07, PDBj:5a07
PDBsum5a07
PubMed26296208
UniProtP38131|KTR4_YEAST Probable mannosyltransferase KTR4 (Gene Name=KTR4)

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