Structure of PDB 4zxw Chain A Binding Site BS02

Receptor Information
>4zxw Chain A (length=443) Species: 1908 (Streptomyces globisporus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PPLSFHQEFLCMFDSGNDGADVGPFGPMYHIVGAWRLTGGIDEETLREAL
GDVVVRHEALRTSLVREGGTHRPEILPAGPAALEVRDLGDVDESERVRRG
EELLNEVESTGLSVRELPLLRAVLGRFDQKDAVLVLIAHHTAADAWAMHV
IARDLLNLYAARRGNPVPPLPEPAQHAEFARWEREAAEAPRVAVSKEFWR
KRLQGARIIGLETDIPRSAGLPKGTAWQRFAVRGELADAVVEFSRAAKCS
PFMTMFAAYQVLLHRRTGELDITVPTFSGGRNNSRFEDTVGSFINFLPLR
TDLSGCASFREVVLRTRTTCGEAFTHELPFSRLIPEVPELMASAASDNHQ
ISVFQAVHAPASEGPEQAGDLTYSKIWERQLSQAEGSDIPDGVLWSIHID
PSGSMAGSLGYNTNRFKDETMAAFLADYLDVLENAVARPDAPF
Ligand information
Ligand IDFRU
InChIInChI=1S/C6H12O6/c7-1-3-4(9)5(10)6(11,2-8)12-3/h3-5,7-11H,1-2H2/t3-,4-,5+,6-/m1/s1
InChIKeyRFSUNEUAIZKAJO-ARQDHWQXSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04OC1C(O)C(OC1(O)CO)CO
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@](O1)(CO)O)O)O)O
CACTVS 3.341OC[CH]1O[C](O)(CO)[CH](O)[CH]1O
OpenEye OEToolkits 1.5.0C(C1C(C(C(O1)(CO)O)O)O)O
CACTVS 3.341OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O
FormulaC6 H12 O6
Namebeta-D-fructofuranose;
beta-D-fructose;
D-fructose;
fructose
ChEMBLCHEMBL604608
DrugBank
ZINCZINC000001529270
PDB chain4zxw Chain C Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4zxw Crystal structure of SgcC5 protein from Streptomyces globisporus
Resolution2.187 Å
Binding residue
(original residue number in PDB)		R243 V371 W391 R393 S410 G421 S422
Binding residue
(residue number reindexed from 1)		R229 V357 W377 R379 S396 G407 S408
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0031177 phosphopantetheine binding
Biological Process
GO:0008610 lipid biosynthetic process
GO:0043041 amino acid activation for nonribosomal peptide biosynthetic process
GO:0044550 secondary metabolite biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4zxw, PDBe:4zxw, PDBj:4zxw
PDBsum4zxw
PubMed
UniProtQ8GMG2

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