Structure of PDB 4zq9 Chain A Binding Site BS02
Receptor Information
>4zq9 Chain A (length=185) Species:
648242
(Adeno-associated virus 2 Srivastava/1982) [
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PGFYEIVIKVPSDISDSFVNWVAEKEWELPPDSDMDLNLIEQAPLTVAEK
LQRDFLTEWRRVSKAPEALFFVQFEKGESYFHMHVLVETTGVKSMVLGRF
LSQIREKLIQRIYRGIEPTLPNWFAVTKTRNGAGGGNKVVDESYIPNFLL
PKTQPELQWAWTNMEQYLSACLNLTERKRLVAQHL
Ligand information
>4zq9 Chain E (length=21) [
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cgcccagcgagcgagcgagcg
Receptor-Ligand Complex Structure
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PDB
4zq9
Structural Insights into the Assembly of the Adeno-associated Virus Type 2 Rep68 Protein on the Integration Site AAVS1.
Resolution
2.6 Å
Binding residue
(original residue number in PDB)
S102 M103 G106 K136 R138 G142 G143 G144 N145
Binding residue
(residue number reindexed from 1)
S94 M95 G98 K128 R130 G134 G135 G136 N137
Binding affinity
PDBbind-CN
: Kd=128nM
Enzymatic activity
Enzyme Commision number
3.6.4.12
: DNA helicase.
External links
PDB
RCSB:4zq9
,
PDBe:4zq9
,
PDBj:4zq9
PDBsum
4zq9
PubMed
26370092
UniProt
P03132
|REP68_AAV2S Protein Rep68 (Gene Name=Rep68)
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