Structure of PDB 4zpr Chain A Binding Site BS02

Receptor Information

>4zpr Chain A (length=235) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

ERLARENHSEIERRRRNKMTAYITELSDMVPTALARKPDKLTILRMAVSH
MKSLTDQELKHLILEAADGFLFIVSGRVVYVSDSVTPVLNQPQSEWFGST
LYDQVHPDDVDKLREQLSRRSFICRMRCVHCTGYVAIGRLQTEFISRHNI
EGIFTFVDHRCVATVGYQPQELLGKNIVEFCHPEDQQLLRDSFQQVVKLK
GQVLSVMFWMRTSSFTFQNPYSDEIEYIICTNTNV

Ligand information

>4zpr Chain D (length=21) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

cacgacccgcacgtacgcagc

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4zpr Structural integration in hypoxia-inducible factors.
Resolution	3.902 Å
Binding residue (original residue number in PDB)	E98 R101 R102
Binding residue (residue number reindexed from 1)	E12 R15 R16

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003700	DNA-binding transcription factor activity
GO:0046983	protein dimerization activity

	Biological Process
GO:0006355	regulation of DNA-templated transcription

	Cellular Component
GO:0005634	nucleus
GO:0005667	transcription regulator complex
GO:0005737	cytoplasm

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External links

PDB	RCSB:4zpr, PDBe:4zpr, PDBj:4zpr
PDBsum	4zpr
PubMed	26245371
UniProt	P53762\|ARNT_MOUSE Aryl hydrocarbon receptor nuclear translocator (Gene Name=Arnt)

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