Structure of PDB 4znx Chain A Binding Site BS02
Receptor Information
>4znx Chain A (length=58) Species:
9606
(Homo sapiens) [
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VTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYI
PSNYVAPV
Ligand information
>4znx Chain F (length=10) Species:
32630
(synthetic construct) [
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APPLPPRNRP
Receptor-Ligand Complex Structure
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PDB
4znx
The role of water molecules in the binding of class I and II peptides to the SH3 domain of the Fyn tyrosine kinase.
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
S114 S115 W120 S135
Binding residue
(residue number reindexed from 1)
S31 S32 W37 S52
Enzymatic activity
Enzyme Commision number
2.7.10.2
: non-specific protein-tyrosine kinase.
External links
PDB
RCSB:4znx
,
PDBe:4znx
,
PDBj:4znx
PDBsum
4znx
PubMed
27599862
UniProt
P06241
|FYN_HUMAN Tyrosine-protein kinase Fyn (Gene Name=FYN)
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