Structure of PDB 4z0c Chain A Binding Site BS02

Receptor Information

>4z0c Chain A (length=709) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

YGFNKCTQYEFDIHHVLCIRKKITNLTEAISDIPRYTTHLNLTHNEIQVL
PPWSFTNLSALVDLRLEWNSIWKIDEGAFRGLENLTLLNLVENKIQSVNN
SFEGLSSLKTLLLSHNQITHIHKDAFTPLIKLKYLSLSRNNISDFSGILE
AVQHLPCLERLDLTNNSIMYLDHSPRSLVSLTHLSFEGNKLRELNFSALS
LPNLTNLSASRNGNKVIQNVYLKTLPQLKSLNLSGTVIKLENLSAKHLQN
LRAMDLSNWELRHGHLDMKTVCHLLGNLPKLETLVFQKNVTNAEGIKQLA
KCTRLLFLDLGQNSDLIYLNDSEFNALPSLQKLNLNKCQLSFINNRTWSS
LQNLTSLDLSHNKFKSFPDFAFSPLKHLEFLSLSRNPITELNNLAFSGLF
ALKELNLAACWIVTIDRYSFTQFPNLEVLDLGDNNIRTLNHGTFRPLKKL
QSLILSHNCLKILEPNSFSGLTNLRSLDLMYNSLSYFHEHLFSGLEKLLI
LKLGFNKITYETTRTLQYPPFIKLKSLKQLNLEGQRHGIQVVPSNFFQGL
GSLQELLLGKNPSVFLDHHQFDPLINLTKLDISGTKDGDRSLYLNASLFQ
NLKRLKILRLENNNLESLVPDMFSSLQSLQVFSLRFNNLKVINQSHLKNL
KSLMFFDVYGNKLQCTCDNLWFKNWSMNTEEVHIPFLRSYPCQQPGSQSL
LIDFDDAMC

Ligand information

>4z0c Chain C (length=13) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

acggaaagacccc

.............

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4z0c Structural basis for specific recognition of single-stranded RNA by Toll-like receptor 13
Resolution	2.3 Å
Binding residue (original residue number in PDB)	E579 T580 R582 H605 Q608 V609 F633 D635 R658
Binding residue (residue number reindexed from 1)	E511 T512 R514 H537 Q540 V541 F565 D567 R590

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:4z0c, PDBe:4z0c, PDBj:4z0c
PDBsum	4z0c
PubMed	26323037
UniProt	Q6R5N8\|TLR13_MOUSE Toll-like receptor 13 (Gene Name=Tlr13)

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