Structure of PDB 4yu3 Chain A Binding Site BS02

Receptor Information

>4yu3 Chain A (length=141) Species: 210647 (Helogale parvula) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

VLSPADKTNIKASWEKIGSHGGEYGAEALERTFLCFPTTKTYFPHFDLSH
GSAQVKAHGKKVADALTNAVGHLDDLPGALSALSDLHAYKLRVDPVNFKL
LSHCLLVTLASHHPAEFTPAVHASLDKFLSSVSTVLTSKYR

Ligand information

InChI=1S/O2/c1-2

MYMOFIZGZYHOMD-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341 OpenEye OEToolkits 1.5.0	O=O

Formula

O2

Name

OXYGEN MOLECULE

PDB chain

4yu3 Chain A Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	4yu3 The crystal structure of mongoose (Helogale parvula) hemoglobin at pH 8.2
Resolution	2.45 Å
Binding residue (original residue number in PDB)	F43 H58
Binding residue (residue number reindexed from 1)	F43 H58
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0004601	peroxidase activity
GO:0005344	oxygen carrier activity
GO:0005506	iron ion binding
GO:0019825	oxygen binding
GO:0020037	heme binding
GO:0031720	haptoglobin binding
GO:0043177	organic acid binding
GO:0046872	metal ion binding

	Biological Process
GO:0015671	oxygen transport
GO:0042744	hydrogen peroxide catabolic process
GO:0098869	cellular oxidant detoxification

	Cellular Component
GO:0005833	hemoglobin complex
GO:0031838	haptoglobin-hemoglobin complex
GO:0072562	blood microparticle

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Cellular Component

External links

PDB	RCSB:4yu3, PDBe:4yu3, PDBj:4yu3
PDBsum	4yu3
PubMed
UniProt	A0A0R4I977

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