Structure of PDB 4xlg Chain A Binding Site BS02

Receptor Information
>4xlg Chain A (length=260) Species: 284593 (Nakaseomyces glabratus CBS 138) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EFQQIPDFYGCYLLQSISKRQSFYIGSTPNPVRRLRQHNGSLSRTKRDGT
RPWEMVAIVYGFPSRIAALQFQHAWQHGTRYISIHHKLAMITSLLKNEYF
RYMDLTLHFFNQKVEEIWKNDKFNVSNYTVSLSQDALTEINNDTIDDIMD
VNEKNMELVQNLYSTTLAEKTKTLLLYKEKIDTGINTCQFCNKIIKHNNI
SENLFAFCRDTSCTFVSHLACAYRYFMSEDTIIPQSPKCPKCYTLLKWCD
VIYYSIKLNK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4xlg Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4xlg Structural and Mechanistic Analysis of the Slx1-Slx4 Endonuclease.
Resolution1.78 Å
Binding residue
(original residue number in PDB)		C242 C247 C279 C282
Binding residue
(residue number reindexed from 1)		C208 C213 C239 C242
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0004520 DNA endonuclease activity
GO:0008821 crossover junction DNA endonuclease activity
GO:0017108 5'-flap endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0006261 DNA-templated DNA replication
GO:0006281 DNA repair
GO:0006310 DNA recombination
Cellular Component
GO:0005634 nucleus
GO:0033557 Slx1-Slx4 complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4xlg, PDBe:4xlg, PDBj:4xlg
PDBsum4xlg
PubMed25753413
UniProtQ6FML9|SLX1_CANGA Structure-specific endonuclease subunit SLX1 (Gene Name=SLX1)

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