Structure of PDB 4xic Chain A Binding Site BS02

Receptor Information
>4xic Chain A (length=59) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALSLTERQIKIWFQN
RRMKWKKEN
Ligand information
Receptor-Ligand Complex Structure
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PDB4xic Entropic Enhancement of Protein-DNA Affinity by Oxygen-to-Sulfur Substitution in DNA Phosphate.
Resolution2.69 Å
Binding residue
(original residue number in PDB)
R3 R5 Q6 Y8 R43 I47 N51
Binding residue
(residue number reindexed from 1)
R2 R4 Q5 Y7 R42 I46 N50
Binding affinityPDBbind-CN: Kd=2.9nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:4xic, PDBe:4xic, PDBj:4xic
PDBsum4xic
PubMed26331260
UniProtP02833|ANTP_DROME Homeotic protein antennapedia (Gene Name=Antp)

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