Structure of PDB 4wzx Chain A Binding Site BS02

Receptor Information
>4wzx Chain A (length=87) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TSARDLLREMARDKPRLLAALEVASAAMAKEEAAGGEQDALDLYQHSLGE
LLLLLAAEPPGRRRELLHTEVQNLMARAEYLKEQVKM
Ligand information
Ligand IDCO
InChIInChI=1S/Co/q+2
InChIKeyXLJKHNWPARRRJB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Co+2]
CACTVS 3.341[Co++]
FormulaCo
NameCOBALT (II) ION
ChEMBL
DrugBankDB14205
ZINC
PDB chain4wzx Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4wzx ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins.
Resolution1.3859 Å
Binding residue
(original residue number in PDB)		H57 E61
Binding residue
(residue number reindexed from 1)		H46 E50
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
External links
PDB RCSB:4wzx, PDBe:4wzx, PDBj:4wzx
PDBsum4wzx
PubMed26011858
UniProtQ6PHR2|ULK3_HUMAN Serine/threonine-protein kinase ULK3 (Gene Name=ULK3)

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