Structure of PDB 4wwc Chain A Binding Site BS02

Receptor Information

>4wwc Chain A (length=213) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

HMNINKQSPIPIYYQIMEQLKTQIKNGELQPDMPLPSEREYAEQFGISRM
TVRQALSNLVNEGLLYRLKGRGTFVSKPKMQGLTSFTEDMKSRGMTPGSR
LIDYQLIDSTEELAAILGCGHSSIHKITRVRLANDIPMAIESSHIPFEIS
RAKQELEPSAATTEEANILGIQKGAPVLLIKRTTYLQNGTAFEHAKSVYR
GDRYTFVHYMDRL

Ligand information

>4wwc Chain F (length=19) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

cagtggtctagaccactgg

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4wwc Structural insight into operator dre-sites recognition and effector binding in the GntR/HutC transcription regulator NagR.
Resolution	2.903 Å
Binding residue (original residue number in PDB)	S36 E37 R38 R48 M49 R52 R66 G69 G71 T72
Binding residue (residue number reindexed from 1)	S37 E38 R39 R49 M50 R53 R67 G70 G72 T73

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0003700	DNA-binding transcription factor activity

	Biological Process
GO:0006355	regulation of DNA-templated transcription
GO:0045892	negative regulation of DNA-templated transcription

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Molecular Function

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Biological Process

External links

PDB	RCSB:4wwc, PDBe:4wwc, PDBj:4wwc
PDBsum	4wwc
PubMed	25564531
UniProt	O34817\|NAGR_BACSU HTH-type transcriptional repressor NagR (Gene Name=nagR)

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