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Receptor Information

>4wsb Chain A (length=699) Species: 1129347 (Influenza A virus (A/little yellow-shouldered bat/Guatemala/060/2010(H17N10))) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MENFVRTNFNPMILERAEKTMKEYGENPQNEGNKFAAISTHMEVCFMYSD
FHFIDLEGNTIVKENDDDNAMLKHRFEIIEGQERNIAWTIVNSICNMTEN
SKPRFLPDLYDYKTNKFIEIGVTRRKVEDYYYEKASKLKGENVYIHIFSF
DGEEMATDDEYILDEESRARIKTRLFVLRQELATALEEEFSYPPTFQRLA
NQSLPPSFKDYHQFKAYVSSFKANGNIEAKLGAMSEKVNAQIESFDPRTI
RELELPEGKFCTQRSKFLLMDAMKLSVLNPAHEGEGIPMKDAKACLDTFW
GWKKATIIKKHEKGVNTNYLMIWEQLLESIKEMEGKFLNLKKTNHLKWGL
GEGQAPEKMDFEDCKEVPDLFQYKSEPPEKRKLASWIQSEFNKASELTNS
NWIEFDELGNDVAPIEHIASRRRNFFTAEVSQCRASEYIMKAVYINTALL
NSSCTAMEEYQVIPIITKCRDTSGQRRTNLYGFIIKGRSHLRNDTDVVNF
ISLEFSLTDPRNEIHKWEKYCVLEIGDMEIRTSISTIMKPVYLYVRTNGT
SKIKMKWGMEMRRCLLQSLQQVESMIEAESAVKEKDMTEPFFRNRENDWP
IGESPQGIEKGTIGKVCRVLLAKSVFNSIYASAQLEGFSAESRKLLLLIQ
AFRDNLDPGTFDLKGLYEAIEECIINDPWVLLNASWFNSFLKAVQLSMG

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4wsb Structural insight into cap-snatching and RNA synthesis by influenza polymerase.
Resolution	2.65 Å
Binding residue (original residue number in PDB)	K281 H326 K328 W363 G366 G368 Q369 A370 P371 Y388 K389 S390 P392 R503 H505 V512 N514 K534 R561 T562 N563 G564 K569
Binding residue (residue number reindexed from 1)	K266 H311 K313 W348 G351 G353 Q354 A355 P356 Y373 K374 S375 P377 R488 H490 V497 N499 K519 R546 T547 N548 G549 K554

Enzyme Commision number

	Molecular Function
GO:0003723	RNA binding
GO:0046872	metal ion binding

	Biological Process
GO:0039694	viral RNA genome replication
GO:0075523	viral translational frameshifting

PDB	RCSB:4wsb, PDBe:4wsb, PDBj:4wsb
PDBsum	4wsb
PubMed	25409151
UniProt	H6QM92

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Structure of PDB 4wsb Chain A Binding Site BS02