Structure of PDB 4wr9 Chain A Binding Site BS02

Receptor Information

>4wr9 Chain A (length=145) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

DEELQTELYEIKHQILQTMGVLSLQGSMLSVGDKVFSTNGQSVNFDTIKE
MCTRAGGNIAVPRTPEENEAIASIAKKYNNYVYLGMIDDQTEGDFHYLDG
ASVSYTNWYPGEPRGQGKEDCVEMYTDGTWNDRGCLQYRLAVCEF

Ligand information

InChI=1S/Ca/q+2

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Ca

Name

CALCIUM ION

PDB chain

4wr9 Chain A Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4wr9 Differential ligand binding specificities of the pulmonary collectins are determined by the conformational freedom of a surface loop
Resolution	2.301 Å
Binding residue (original residue number in PDB)	D171 E175 Q199 E202 D203
Binding residue (residue number reindexed from 1)	D88 E92 Q116 E119 D120
Annotation score	4

Enzymatic activity

Enzyme Commision number

External links

PDB	RCSB:4wr9, PDBe:4wr9, PDBj:4wr9
PDBsum	4wr9
PubMed	28719181
UniProt	P08427\|SFTPA_RAT Pulmonary surfactant-associated protein A (Gene Name=Sftpa1)

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