Structure of PDB 4wn0 Chain A Binding Site BS02

Receptor Information
>4wn0 Chain A (length=277) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GYRSCNEIKSSDSRAPDGIYTLATEDGESYQTFCDMTTNGGGWTLVASVH
ENNMFGKCTVGDRWSTQQGNMLQNPEGDGNWANYATFGLPEGATSDDYKN
PGYYDIEAKNLALWHVPNKTPMVMWRNSSILRYRTQNGFLTEEGGNLFEL
YKKYPVKYDIGKCLADNGPAVPVVYDLGSAEKTASLYSPNGRSEFTPGFV
QFRAVNSERATLALCAGVKVKGCNVEHHCIGGGGYIPEGSPRQCGDFAAL
DWDGYGTNLGWSASKQIIEAAVMLFYR
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain4wn0 Chain A Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4wn0 Structures of Xenopus Embryonic Epidermal Lectin Reveal a Conserved Mechanism of Microbial Glycan Recognition.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		H115 G126 D162 D311
Binding residue
(residue number reindexed from 1)		H50 G61 D97 D246
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0030246 carbohydrate binding
GO:0046872 metal ion binding
GO:0070492 oligosaccharide binding
Biological Process
GO:0034214 protein hexamerization
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0030133 transport vesicle
GO:0030141 secretory granule
GO:0031410 cytoplasmic vesicle

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4wn0, PDBe:4wn0, PDBj:4wn0
PDBsum4wn0
PubMed26755729
UniProtQ5PPM0|ITLN1_XENLA Intelectin-1 (Gene Name=itln1)

[Back to BioLiP]