Structure of PDB 4ud7 Chain A Binding Site BS02

Receptor Information
>4ud7 Chain A (length=97) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQYIMTK
RLYDAAQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVN
Ligand information
Receptor-Ligand Complex Structure
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PDB4ud7 Benzene Probes in Molecular Dynamics Simulations Reveal Novel Binding Sites for Ligand Design.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		G15 Q18
Binding residue
(residue number reindexed from 1)		G1 Q4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Gene Ontology
Biological Process
GO:0043066 negative regulation of apoptotic process
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:4ud7, PDBe:4ud7, PDBj:4ud7
PDBsum4ud7
PubMed27532490
UniProtQ00987|MDM2_HUMAN E3 ubiquitin-protein ligase Mdm2 (Gene Name=MDM2)

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