Structure of PDB 4u4t Chain A Binding Site BS02

Receptor Information
>4u4t Chain A (length=444) Species: 511145 (Escherichia coli str. K-12 substr. MG1655) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VITDWRPEDPAFWQQRGQRIASRNLWISVPCLLLAFCVWMLFSAVAVNLP
KVGFNFTTDQLFMLTALPSVSGALLRVPYSFMVPIFGGRRWTAFSTGILI
IPCVWLGFAVQDTSTPYSVFIIISLLCGFAGANFASSMANISFFFPKQKQ
GGALGLNGGLGNMGVSVMQLVAPLVVSLSIFAVFGSQGVKQPDGTELYLA
NASWIWVPFLAIFTIAAWFGMNDLATQLPVLKRGHLWIMSLLYLATFGSF
IGFSAGFAMLSKTQFPDVQILQYAFFGPFIGALARSAGGALSDRLGGTRV
TLVNFILMAIFSGLLFLTLPTDGQGGSFMAFFAVFLALFLTAGLGSGSTF
QMISVIFRKLTMDRVKAEGGSDERAMREAATDTAAALGFISAIGAIGGFF
IPKAFGSSLALTGSPVGAMKVFLIFYIACVVITWAVYGRHSKKL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4u4t Chain A Residue 502 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4u4t Structural basis for dynamic mechanism of nitrate/nitrite antiport by NarK
Resolution2.4 Å
Binding residue
(original residue number in PDB)		H255 H460
Binding residue
(residue number reindexed from 1)		H235 H440
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005452 solute:inorganic anion antiporter activity
GO:0015112 nitrate transmembrane transporter activity
GO:0015113 nitrite transmembrane transporter activity
GO:0022857 transmembrane transporter activity
Biological Process
GO:0015706 nitrate transmembrane transport
GO:0015707 nitrite transport
GO:0042128 nitrate assimilation
GO:0043602 nitrate catabolic process
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4u4t, PDBe:4u4t, PDBj:4u4t
PDBsum4u4t
PubMed25959928
UniProtP10903|NARK_ECOLI Nitrate/nitrite antiporter NarK (Gene Name=narK)

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