Structure of PDB 4tz6 Chain A Binding Site BS02

Receptor Information
>4tz6 Chain A (length=504) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKLIHVPKEEVTLDSLLEEGVLDKEIHKAITRMEFPGLTPVQQKTIKPIL
SSEDHDVIARAKTGTGKTFAFLIPIFQHLINTKFDSQYMVKAVIVAPTRD
LALQIEAEVKKIHDMNYGLKKYACVSLVGGTDFRAAMNKMNKLRPNIVIA
TPGRLIDVLEKYSNKFFRFVDYKVLDEADRLLEIGFRDDLETISGILNEK
NSKSADNIKTLLFSATLDDKVQKLANNIMNKKECLFLDTVDKNEPEAHER
IDQSVVISEKFANSIFAAVEHIKKQIKERDSNYKAIIFAPTVKFTSFLCS
ILKNEFKKDLPILEFHGKITQNKRTSLVKRFKKDESGILVCTDVGARGMD
FPNVHEVLQIGVPSELANYIHRIGRTARSGKEGSSVLFICKDELPFVREL
EDAKNIVIAKQEKYEPSEEIKSEVLEAVTEEPEDISDIVISLISSYRSCI
KEYRFSERRILPEIASTYGVLLNDPQLKIPVSRRFLDKLGLSRSPIGKAM
FEIR
Ligand information
Ligand IDBEF
InChIInChI=1S/Be.3FH/h;3*1H/q+2;;;/p-3
InChIKeyOGIAHMCCNXDTIE-UHFFFAOYSA-K
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[Be-](F)(F)F
ACDLabs 10.04
CACTVS 3.341		F[Be-](F)F
FormulaBe F3
NameBERYLLIUM TRIFLUORIDE ION
ChEMBL
DrugBank
ZINC
PDB chain4tz6 Chain A Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4tz6 Molecular insights into RNA and DNA helicase evolution from the determinants of specificity for a DEAD-box RNA helicase.
Resolution3.209 Å
Binding residue
(original residue number in PDB)		K158 E268 R466 R469
Binding residue
(residue number reindexed from 1)		K67 E177 R375 R378
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:4tz6, PDBe:4tz6, PDBj:4tz6
PDBsum4tz6
PubMed25497230
UniProtP15424|MS116_YEAST ATP-dependent RNA helicase MSS116, mitochondrial (Gene Name=MSS116)

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