Structure of PDB 4tn1 Chain A Binding Site BS02

Receptor Information
>4tn1 Chain A (length=330) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNKDNLRSPICCILGHVRTGKTKLLDKIRQTNVQEGEAGGITQQIGATYF
PVEAIKQKTAVVNKDGKFEFKVPGLLIIDTPGHESFSNLRSRGSSLCNIA
ILVVDIMHGLEPQTIESLRLLRERKTPFVVALNKIDRLYGWKKIENNGFR
ESFALQNKAVQNEFRNRLDQVKLQFAEQGFNSELFYENKNFARYVSLVPT
SAHTGEGIPDMLKLIVQLCQERMASSLMYLSELQATVLEVKAIEGFGVTI
DVILSNGILREGDRIVLCGLEGPIKTNIRALLTPAPMRELRIKGQYIHHK
EVKAAQGVKISAPGLEGAIAGSRLLVVGPD
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4tn1 Chain A Residue 902 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4tn1 A monovalent cation acts as structural and catalytic cofactor in translational GTPases.
Resolution2.75 Å
Binding residue
(original residue number in PDB)
T537 T557
Binding residue
(residue number reindexed from 1)
T22 T42
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.3: protein-synthesizing GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:4tn1, PDBe:4tn1, PDBj:4tn1
PDBsum4tn1
PubMed25225612
UniProtG0S8G9|IF2P_CHATD Eukaryotic translation initiation factor 5B (Gene Name=CTHT_0029840)

[Back to BioLiP]