Structure of PDB 4tmt Chain A Binding Site BS02

Receptor Information
>4tmt Chain A (length=342) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNKDNLRSPICCILGHVATGKTKLLDKIRQTNVQEGEAGGITQQIGATYF
PVEAIKQKTAVVNKDGKFEFKVPGLLIIDTPGHESFSNLRSRGSSLCNIA
ILVVDIMHGLEPQTIESLRLLRERKTPFVVALNKIDRLYGWKKIENNGFR
ESFALQNKAVQNEFRNRLDQVKLQFAEQGFNSELFYENKNFARYVSLVPT
SAHTGEGIPDMLKLIVQLCQERMASSLMYLSELQATVLEVKAIEGFGVTI
DVILSNGILREGDRIVLCGLEGPIKTNIRALLTPAPMRELRIKGQYIHHK
EVKAAQGVKISAPGLEGAIAGSRLLVVGPDDDEEELEEEVES
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4tmt Chain A Residue 902 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4tmt A monovalent cation acts as structural and catalytic cofactor in translational GTPases.
Resolution1.58 Å
Binding residue
(original residue number in PDB)		T537 T557
Binding residue
(residue number reindexed from 1)		T22 T42
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.3: protein-synthesizing GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:4tmt, PDBe:4tmt, PDBj:4tmt
PDBsum4tmt
PubMed25225612
UniProtG0S8G9|IF2P_CHATD Eukaryotic translation initiation factor 5B (Gene Name=CTHT_0029840)

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