Structure of PDB 4rke Chain A Binding Site BS02

Receptor Information
>4rke Chain A (length=176) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GAMGMSYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGAR
MITIDGKQIKLQIWDTAGLEAFRSITRSYYRGAAGALLVYDITRRETFNH
LTTWLEDARQHSNSNMVIMLIGNKSDLDSRREVKKEEGEAFAREHGLVFM
ETSARTAANVEEAFINTAKEIYEKIQ
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4rke Chain A Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4rke Structures of Drosophila melanogaster Rab2 and Rab3 bound to GMPPNP.
Resolution2.0006 Å
Binding residue
(original residue number in PDB)		S20 T38
Binding residue
(residue number reindexed from 1)		S24 T42
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:4rke, PDBe:4rke, PDBj:4rke
PDBsum4rke
PubMed25615965
UniProtO18333|RAB2_DROME Ras-related protein Rab-2 (Gene Name=Rab2)

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