Structure of PDB 4r8c Chain A Binding Site BS02

Receptor Information
>4r8c Chain A (length=84) Species: 226900 (Bacillus cereus ATCC 14579) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QVLFVLTILTLISGTIFYSTVEGLRPIDALYFSVVTLTTVGETPPPQTDF
GKIFTILYIFIGIGLVFGFIHKLAVNVQLPSILS
Ligand information
Ligand IDGLY
InChIInChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChIKeyDHMQDGOQFOQNFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C(=O)O)N
CACTVS 3.341NCC(O)=O
ACDLabs 10.04O=C(O)CN
FormulaC2 H5 N O2
NameGLYCINE
ChEMBLCHEMBL773
DrugBankDB00145
ZINCZINC000004658552
PDB chain4r8c Chain A Residue 209 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4r8c A structural, functional, and computational analysis suggests pore flexibility as the base for the poor selectivity of CNG channels.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		R49 I51
Binding residue
(residue number reindexed from 1)		R25 I27
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005267 potassium channel activity
Biological Process
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4r8c, PDBe:4r8c, PDBj:4r8c
PDBsum4r8c
PubMed26100907
UniProtQ81HW2

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